Management of Combined Therapy (Ceritinib, A. cinnamomea, G. lucidum, and Photobiomodulation) in Advanced Non-Small-Cell Lung Cancer: A Case Report

Abstract

The 5-year survival rate of non-small-cell lung cancer (NSCLC) is still low (<21%) despite recent improvements. Since conventional therapies have a lot of side effects, combined therapy is strongly recommended. Here, we report a patient with advanced NSCLC who received combined therapy, including ceritinib, photobiomodulation (PBM), ACGL (Antrodia cinnamomea (A. cinnamomea), and Ganoderma lucidum (G. lucidum)). Based on combined therapy, suitable doses of A. cinnamomea, G. lucidum, and PBM are important for tumor inhibition. This case report presents clinical evidence on the efficacy of combined therapy in advanced NSCLC patients, including computed tomography (CT) scan, magnetic resonance imaging (MRI), carcinoembryonic antigen (CEA), and blood tests. The effective inhibition of human lung adenocarcinoma cells is demonstrated. Our case highlights important considerations for PBM and ACGL applications in NSCLC patients, the side effects of ceritinib, and long-term health maintenance.

Figures

Figure 1

( a ) Multiple pulmonary…

Figure 1

( a ) Multiple pulmonary metastases of bilateral lung by chest CT. The…

Figure 1 (a) Multiple pulmonary metastases of bilateral lung by chest CT. The CT scans of the patient whom received (b) 2 and (c) 10 months of combined therapy.

Figure 2

Schematics for the position of…

Figure 2

Schematics for the position of 830 nm laser on NSCLC patients. ( a…

Figure 2 Schematics for the position of 830 nm laser on NSCLC patients. (a) Shaoshang (LU 11), Zhongchong (PC 9), Guanchong (TE 1), apex of lung and Feishu (BL 13) acupoints. The abnormal of ASL, ALT, and BUN levels can be modulated by 830 nm laser radiated on (b) Ganshu (BL 18) and Yongquan (KI 1) acupoints. (c) Tianshu (ST 25) and Zusanli (ST 36) acupoints and stomach area can be used for severe diarrhea treatment. (d) Shaoshang (LU 11) and Lieque (LU 07) acupoints can be used for severe dizziness treatment (The acupoints are marked by red arrows). Illustration created with BioRender.com (accessed on 8 April 2022).

Figure 3

( a ) Volume of…

Figure 3

( a ) Volume of tumor size of adenocarcinoma in situ. ( b…

Figure 3 (a) Volume of tumor size of adenocarcinoma in situ. (b) Blood test for CEA marker. (c) Blood test of AST, ALT, BUN, and CRE. (d) Lung meridian energy level measurement (The measurement values at different time are represented in different color circles).